What is a human person? Human freedom? Human well-being? Human purpose? What sort of society enables persons to flourish? Few contemporary sociologists ask these big questions any longer because most have adopted a deeply flawed understanding of social science—positivism. This is because positivism is committed to materialist reductionism, causal determinism, moral relativism and methodological individualism, and must therefore deny the substantial reality of human persons, human freedom, human purpose and social goods. Reopening the social sciences to the big questions once again requires that it be rebuilt on a new foundation. We believe that foundation should be Critical Realism (CR). CR is a form of scientific realism. For CR, the goal of science is to understand the hidden structures and powers that give rise to the order we observe in the world. CR is also a form of moral realism. It understands human persons as members of a species that has evolved certain capacities and dispositions whose development and exercise is crucial to their individual and collective well-being. We have developed a multi-pronged strategy to increase the profile of CR within American sociology and, eventually, within other fields and regions as well. It includes: 1) summer schools on CR for graduate students; 2) advanced seminars on CR for younger faculty; 3) research working groups focused on particular subfields within the discipline, such as ethnography and historical sociology; 4) publication of accessible and affordable texts on CR; 5) development of undergraduate and graduate curricula focused on the sociology of human flourishing ("positive sociology"). Through these activities, we hope to create a broad network of scholars who can fundamentally and lastingly change the social sciences.