Sean A. Spence is professor of general adult psychiatry at the University of Sheffield. His principle research focus is the regulation of voluntary behavior in healthy populations and those affected by neuropsychiatric disease. He serves as honorary consultant psychiatrist to the Sheffield Care Trust and consultant psychiatrist to the Sheffield Homelessness Assessment and Support Team. Educated at St. Mary and St. Joseph’s Catholic School and Salvatorian College in Harrow, he studied medicine at Guy’s Hospital in London where he earned an intercalated honors B.Sc. and a bachelor of medicine and a bachelor of surgery degree in 1986. After further training at various London hospitals, Dr. Spence accepted a Medical Research Council (MRC) clinical training fellowship to work on the MRC cyclotron unit at Hammersmith Hospital while also serving as honorary lecturer in psychiatry at the Imperial College School of Medicine, London University. He was named a Dewitt Wallace Visiting Research Fellow at New York Hospital-Cornell Medical Center’s Functional Neuroimaging Laboratory in 1999 and awarded an M.D. by University College, London, the next year. Dr. Spence joined the Sheffield psychiatry faculty as a clinical senior lecturer in 2000 and was appointed to his present position in 2005. Elected a fellow of the Royal College of Psychiatrists last year, he is a past recipient of Guy’s Gillespie Prize in Psychological Medicine, the Charing Cross Rotation Audit Prize, and the Royal College of Psychiatrists Research Prize and Medal, as well as several awards for papers and essays and numerous travel grants. He will hold the Royal Australian and New Zealand College of Psychiatrists’ Traveling Professorship in 2008. Dr. Spence is a co-author of more than fifty papers published in scientific journals and the co-editor (with Peter W. Halligan) of Pathologies of Body, Self and Space (2002) and, most recently, (with Anthony S. David) Voices in the Brain: The Cognitive Neuropsychiatry of Auditory Verbal Hallucinations, which was published by Psychology Press in 2004. He is the co-author (with Ann Mortimer) of Managing Negative Symptoms of Schizophrenia (2001).